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SFRBM's 13th Annual Meeting
November 15-19, 2006
Adam's Mark Denver
Denver, Colorado USA
Wednesday, November 15, 2006
Pre-Meeting Workshop I:
The Thiol Group in Oxidative Stress and Redox Signaling
Chairs: Neil Hogg, Ph.D., Medical College of Wisconsin, Milwaukee, WI and
Yvonne Janssen-Heininger, Ph.D., University of Vermont
8:00 am – 8:35 am
The Biological Chemistry of Thiols: Reactions of Thiols with Biologically Relevant Oxidants and the Reactions of Thiyl Radicals Formed on Oxidation
Peter Wardman, Ph.D. Gray Cancer Institute, UK
8:35 am – 9:10 am
Analytical Assessment of Thiols in Biological Systems
Henry Forman, Ph.D., University of California - Merced
9:10 am – 9:45 am
Biologically Relevant Thiol Modifications and Effecits on Enzyme Function
Christine Winterbourn, Ph.D., Christchurch School of Medicine, New Zealand
9:45 am – 10:15 am
Break
10:15 am – 10:50 am
Proteomic Assessment of Thiol Modifications
Victor Darley-Usmar, Ph.D., University of Alabama at Birmingham
10:50 am – 11:25 am
Measuring the Poise of the Thiol/Disulfide in vivo
Dean P. Jones, Ph.D., Emory University
11:25 am – 12:00 pm
Protein Disulfide Isomerase in Cell Signaling
Bulent Mutus, Ph.D., University of Windsor, Canada
12:00 pm – 1:30 pm
Lunch
1:30 pm – 2:05 pm
Cell Signaling Through the Thiol Group
Yvonne Janssen-Heininger, Ph.D., University of Vermont
2:05 pm – 2:40 pm
The NRF2/Keap1 Pathway
Akira Kobayashi, Ph.D., University of Tsukuba - Japan
2:40 pm – 3:15 pm
Novel Thiol Modifications Relevant to Signal Transduction
Richard Cohen, MD, Boston University Medical Center
3:15 pm – 4:30 pm
One-on-one Poster Session
Pre-Meeting Workshop II
Your Array of Possibilities: A Full Spectrum of Careers in Science
Organized by Louise B. Giles, MD, University of Manitoba and
Asma Zaidi, Ph.D., University of Kansas
3:15 pm
Welcome and Overview
3:20 pm – 4:00 pm
Presentation: Left Lane, Right Lane, When to Exit for Your Destination
4:00 pm – 5:35 pm
Discussion: led by senior scientists that represent the spectrum of careers available to young scientists in the Society.
5:35 pm – 5:45 pm
Wrap-up
Pre-Meeting Workshop III
Grantsmanship Workshop for Young Investigators
Ed Postlewait, Ph.D., University of Alabama at Birmingham
3:15 pm – 5:45 pm
6:00 pm – 7:00 pm
SFRBM Annual Membership Meeting
7:00 pm – 9:00 pm
Opening Reception
9:00 pm – 12:00 am
Hospitality Room
Thursday, November 16, 2006
Sunrise Free Radical School
Chairs: Tak Yee Aw, Ph.D., LSU Health Sciences Center and
Kenneth Hensley, Ph.D., Oklahoma Medical Research Foundation
8:00 am – 8:45 am
The Basics of Free Radical Chemistry and Their Biology
Arlan Richardson, Ph.D., University of Texas Health Science Center
8:45 am – 9:30 am
In vivo/In vitro Measurement of Angiogenesis
Kenneth Walsh, Ph.D., Boston University School of Medicine
Plenary Session
Redox Regulation of Angiogenesis and Vascular Reactivity
Chairs: Christopher G. Kevil, Ph.D., LSU Health Sciences Center and
Rakesh P. Patel, Ph.D., University of Alabama at Birmingham
10:00 am – 10:30 am
eNOS Regulation of Angiogenesis in Health and Disease
William Sessa, Ph.D., Yale University School of Medicine
10:30 am – 11:00 am
Role of ROS/RNS on eNOS Dysfunction and Vascular Reactivity
David Lefer, Ph.D., Albert Einstein College of Medicine
11:00 am – 11:30 am
Break
11:30 am – 12:00 pm
Reactive Oxygen Species Regulation of Angiogenesis
Masuko Ushio-Fukai, Ph.D.,University of Illinois at Chicago
12:00 pm – 12:30 pm
Cellular Mechanisms of Redox Processes Underlying Vascular Response to Injury
Francisco Laurindo, MD, University of São Paolo Medical School
2:00 pm – 4:40 pm
Oral presentations from submitted abstracts (3 concurrent sessions)
4:45 pm – 6:30 pm
Formal poster presentations
6:30 pm – 8:00 pm
FRBM Editorial Board Reception
7:00 – 9:00 pm
Opening Doors Event
Organized by Rama Dey-Rao, Ph.D., Roswell Park Cancer Institute and
Maureen Gwinn, Ph.D., NIOSH, Women in Science Committee
sponsored by Lifeline Therapeutics
Featured speaker: Dr. Cynthia Robbins-Roth, editor and author of “Alternative Careers in Science: Leaving the Ivory Tower”
9:00 pm – 12:00 am
Hospitality Room
Friday, November 17, 2006
Sunrise Free Radical School
Chairs: Tak Yee Aw, Ph.D., LSU Health Sciences Center and
Kenneth Hensley, Ph.D., Oklahoma Medical Research Foundation
8:00 am – 8:45 am
Oxidative Stress at Respiratory Tract Surfaces: Focus Cystic Fibrosis
Carroll Cross, MD, University of California at Davis
8:45 am – 9:30 am
Oxygen, Redox Signaling and Lung Injury
Lin Mantell, MD, Ph.D., The Feinstein Institute for Medical Research, New York
Plenary Session
Oxidants and Antioxidants in Environmental and Occupational Lung Disease
Chairs: Carl White, MD, National Jewish Medical & Research Center and
Carroll Cross, MD, University of California at Davis
10:00 am – 10:30 am
Ozone in Model Systems and In Vivo
Edward M. Postlethwait, Ph.D., University of Alabama at Birmingham
10:30 am – 11:00 am
Ultrafine Particles in Lung Injury and Inflammation
Günter Oberdörster, DVM, Ph.D., University of Rochester
11:00 am – 11:30 am
Break
11:30 am – 12:00 pm
Cigarette Smoke and Oxidant Injury
Kent E. Pinkerton, DVM, Ph.D., University of California at Davis
12:00 am – 12:30 pm
Genetic Susceptibility to Environmental Oxidant Lung Injury
Steven R. Kleeberger, Ph.D., NIEHS
2:00 pm – 4:40 pm
Oral presentations from submitted abstracts (3 concurrent sessions)
4:45 pm – 6:30 pm
Formal poster presentations
9:00 pm – 12:00 am
Hospitality Room
Saturday, November 18, 2006
Sunrise Free Radical School
Chairs: Tak Yee Aw, PhD, LSU Health Sciences Center and
Kenneth Hensley, PhD, Oklahoma Medical Research Foundation
8:00 am – 8:45 am
Mitochondria – More Than Just ATP Cows
Paul Brookes, Ph.D., University of Rochester
8:45 am – 9:30 am
Mitochondrial ROS – Integrators of Protective and Pathologic Cell Signaling
Alicia Kowaltowski, Ph.D., University of São Paulo
Plenary Session
Oxidative Mitochondrial Modifications: Proteins, DNA, & Lipids
Chairs: Aimee Landar, Ph.D., University of Alabama Birmingham and
Paul Brookes, Ph.D., University of Rochester
10:00 am – 10:30 am
Mitochondrial Dysfunction in Infectious Diseases: Insights from Genomics and Proteomics Analysis
Nisha Jain Garg Ph.D., University of Texas Medical Branch
10:30 am – 11:00 am
Proteomic and Genomic Analysis of Mitochondria-to-Nucleus Retrograde Response in Human Cancer Cells
Keshav Singh, Ph.D., Roswell Park Cancer Institute
11:00 am – 11:30 am
Break
11:30 am – 12:00 pm
Cardiac Mitochondrial Proteomics – Linking Proteins to Phenotypes
PeiPei Ping, Ph.D., UCLA
12:00 pm – 12:30 pm
The Interaction of Oxidized Lipids with Mitochondrial Proteins: Mechanisms and Biological Implications
Aimee Landar, Ph.D., University of Alabama at Birmingham
12:40 pm – 2:00 pm
Mentoring Luncheon
2:00 pm – 4:40 pm
Oral presentations from submitted abstracts (3 concurrent sessions)
4:45 pm – 6:30 pm
Formal poster presentations
7:30 pm – 9:30 pm
Closing/Awards Banquet
9:30 pm – 12:00 am
Hospitality Room
Sunday, November 19, 2006
Sunrise Free Radical School
Chairs: Tak Yee Aw, Ph.D., LSU Health Sciences Center and
Kenneth Hensley, Ph.D., Oklahoma Medical Research Foundation
8:00 am – 8:35 am
Redox, Kinetic, and Biological Necessities to Create an Effective Metalloenzyme-mimetic
in the Oxidative Stress Arena
James Crapo, MD, National Jewish Medical and Research Center
8:35 am – 9:15 am
SFRBM Lifetime Achievement Award Lecture
Adaptive Responses to Acute, Chronic or Repetitive Oxidative Stresses in Health, Disease & Aging
Kelvin Davies, Ph.D. University of Southern California
9:15 am – 9:55 am
SFRBM Discovery Award Lecture
How the Serendipitous Discovery of Isoprostanes Advanced the Field of Free Radical Biology and Medicine
L. Jackson Roberts, MD and Jason Morrow, MD, Vanderbilt University
Plenary Session
Organometallic Complexes as Therapeutic Agents in Human Disease
Chairs: Lee Ann MacMillan-Crow, Ph.D., University of Arkansas for Medical Sciences and
Brian Day, Ph.D. National Jewish Medical Center
10:00 am – 10:25 am
Biomedical Applications of Texaphyrins
Jonathan Sessler, Ph.D., University of Texas
10:25 am – 10:50 am
Organometallic Compounds in Neurodegenerative Disease: Oxidant Scavenging and More
John Crow, Ph.D., University of Arkansas
10:50 am – 11:15 am
Metalloporphyrin Catalytic Antioxidants in Experimental Parkinson's Disease
Manisha Patel, Ph.D., University of Colorado
11:15 am – 11:40 am
Use of Synthetic Catalytic Scavenger Technology to Combat Oxidative Stress
Susan Doctrow, Ph.D., Proteome Systems, Inc.
11:40 am – 12:05 pm
Use of Catalytic Antioxidants in Acute Lung Injury
Brian Day, Ph.D., National Jewish Medical & Research Center
ADJOURN
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