SFRBM Webinar

SOCIETY FOR FREE RADICAL BIOLOGY AND MEDICINE
8365 Keystone Crossing
Suite 107
Indianapolis, IN 46240
(317) 205-9482
(317) 205-9481 Fax
info@sfrbm.org

Free Radical School Virtual Seminar Series

SFRBM is proud to introduce a new educational benefit for members - the Free Radical School Virtual Seminar series. SFRBM plans to offer these virtual sessions on a quarterly basis, providing valuable education on a wide range of topics. The sessions are open to SFRBM members only and are offered at no charge.

Redox Signaling Through Protein Cysteine Residues
Wednesday, February 24, 2010
1:00 pm Eastern (12:00 pm Central, 11:00 am Mountain,
10:00 am Pacific; this is 18:00 GMT/UTC) International attendees should convert the time accordingly.
Length of session: 45 minutes
Speaker: Neil Hogg, Ph.D., Medical College of Wisconsin

Program Overview:
•General Redox signaling mechanisms – Cysteine modifications that can affect
protein function (S-thiolation, oxidation, S-nitrosation, iron sulfur cluster disruption,
thiyl radical formation) with a focus on thiyl radicals and Fe/S
•Examples of redox signaling mechanisms – Prokaryotic examples: Oxy R and Sox
R/S as prototypic vicinal thiol and iron/S cluster targets
•YAP1 in yeast as an a process with intermediary complexity
•Higher eukaryotic examples: Nrf2/Keep1 (thiol modification leading to transcriptional
regulation), ASK1/TRX (link between oxidative signaling and phosphorylation cascades
to control gene expression)
•Food for thought: Gain in function vs loss of function – does 1% modification of a
particular thiol matter?

Program Format:
Members can attend a SFRBM Virtual Free Radical School session right from
your office or home. All you need to participate is a telephone and/or a computer with
high speed internet connection. The audio is delivered over the telephone (toll-free)
or the internet. Registrants will be provided call in/login information 2-3 days prior to
the session and a URL to access the presentation right on the web in real time.

Cost:
There is no cost for SFRBM members to participate. The webinar is open to SFRBM
members only.

Click HERE to register.

ABOUT THE SPEAKER:
Dr. Hogg's research focuses on nitric oxide and oxidative signaling mechanisms,
particularly S-nitrosation and thiol oxidation, bioactivation of nitrite in biological systems
and hemoglobin and oxidative stress in Sickle Cell disease. He is currently the Director
of the Redox Biology program at the Medical College of Wisconsin where he has been on
faculty since 1996.

Dr. Hogg is a former SFRBM council member and currently serves on the Free Radical
Biology and Medicine (FRBM) journal Editorial Board.

October 2009 Webinar Now Available

The Many Faces of Oxygen, Sulfur, & Selenium in Redox Biology
Virtual Free Radical School Webinar - October 2009
Speaker: Garry Buettner, Ph.D., The University of Iowa
Length: 50 minutes

CLICK HERE to download the presentation.

Questions?
Contact SFRBM at (317) 205-9482 or via email at info@sfrbm.org.